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Dr. Morse's Cellular Botanicals GI Broom Fine Powdered Blend Review

GI Broom Fine Powdered Blend is a dietary supplement from Dr. Morse's Cellular Botanicals, listed in the NIH Dietary Supplement Label Database (DSLD ID 302929) with a date entered of 22 November 2023 and market status On Market. The product is classified with the supplement form Powder and the product type Other Combinations. Its dietary claim is listed as All Other, Structure/Function, and its intended target group is Adults (18 - 50 Years). The net contents are 7 ounces (198.45 grams). The label lists a serving size of 1 teaspoon with 32 servings per container. Per serving the label lists 20 calories, less than 5 mg cholesterol (2% DV), 5 g total carbohydrates (2% DV), 4 g dietary fiber (13% DV), less than 1 g protein, 6.1 mcg vitamin D (31% DV), 80 mg calcium (6% DV), 2.2 mg iron (12% DV), 20 mg sodium (1% DV), and 110 mg potassium (2% DV). A proprietary blend of 6.2 g is listed, containing psyllium husk, chickweed, cascara sagrada, plantain, fenugreek, marshmallow, slippery elm, white oak, irish moss, bayberry, mullein, activated charcoal, ginger, acerola cherry, aloe vera, and cinnamon. The suggested use is to take 1 rounded teaspoon in 4-6 oz of water or fresh pressed grape or apple juice once daily, either mid-morning or bedtime, followed immediately by 4-6 oz of water. The label advises not to consume within 2 hours of meals and or supplements. The FDA statement of identity is Dietary Supplement. The label includes the standard FDA disclaimer that statements have not been evaluated by the Food and Drug Administration and that the product is not intended to diagnose, treat, cure or prevent any disease. The formulation statements say the brand supports cellular regeneration with its tissue specific formulas, were created with over 45 years of experience, are made in the USA with global ingredients, and are made with organic, wildcrafted or consciously cultivated herbs. The manufacturer is listed as Western Botanicals FL, LLC, Spanish Fork, UT. The page also lists other labels from the same brand, including GI Renew (1 - Normal) Capsules, and other labels that share an ingredient. This page is a label record only and does not show a retail price, a barcode number, or customer reviews.

Product Focus: Regularity: Long-Term ReliefAlso covers:Digestion
Tier ⓘ
Tier 4 · Rank 6
Tier 4 · Emerging. A promising mechanism or animal data, with thin human evidence so far. Rank 6 within Tier 4 for Regularity: Long-Term Relief; 8 of 14 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
59 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
98% of 29
Biohacker Mentions
9 of 10

Study, Trial or Testing Result Summary

Members Only76 human studies · 22 improved

4 of these 76 human studies gave the ingredient by drip, not by mouth.

76 human studies22 improved40 no effect122,219 people studied

This product's main ingredients, including psyllium husk and cascara sagrada, sit inside a 6.2 gram proprietary blend with no stated amounts, and no study findings on them were provided, so their effect on regularity cannot be judged here. The listed nutrients are all small amounts, well below the doses studied. For calcium, large five-year trials found that 1 gram or 1200 milligrams a day led to more constipation than placebo [1][2], and a two-year trial in men found no difference [3]. Small trials at 500 milligrams a day found no change in stool frequency [4][5]. Benefits seen in constipated children came from calcium polycarbophil, a fiber, not plain calcium [6]. Iron does not help regularity and tends to cause constipation at much higher doses [7][8]. No trial has tested vitamin D alone for constipation, and a review in children found it did not help [9]. No study has tested potassium for regularity [10]. Overall, the evidence given does not show this product helps with regularity. Animal and cell studies are never counted.

See all 76 studies →Hide the studies

Review Totals and Summary

Members Only29 reviews · 98% positive
29 reviews · Google Shopping 29
98% positive0% neutral2% negative

Public customer feedback for this product is very sparse. Many retailer pages show no reviews. The one review I found, on an aggregator page for the capsule version, was enthusiastic. Because of that, I can't offer a reliable summary of global customer opinion, and the themes below are tentative. The reviewer calls it an absolute must-have. They use it as a "rescue" after eating junk food, taking it to help the body eliminate smoothly. They also say that paired with a fruit-heavy diet it cleans out the GI tract thoroughly. The praise therefore centers on perceived effectiveness for bowel movements and on its use alongside Dr. Morse's diet philosophy. I found no verified complaints. Based on how similar fiber, cascara and charcoal blends are generally described, the likely concerns would be loose stools, cramping, a gritty or earthy texture in powder form, and the price. I did not see any customers report these for this product, so treat them as guesses and not as findings. I also found no independent professional analyses, lab tests or clinical studies of this exact formula. Retailer copy is promotional and uses soft "supports digestive health" language. For a fuller picture, check larger retail listings or forums, such as the brand's own store, Amazon, or Reddit communities on Dr. Morse's protocols. I could not reach those with my search. Reviews there may mention how quickly it works, how strong it is, taste and mixability, and any digestive discomfort.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Calcium is the main ingredient, and the panel is lukewarm on it: three of ten recommend it, while most others simply mention it without advising for or against. Those who recommend it describe it as a key mineral for bones, and also for nerves, muscles and the heart, with one suggesting 1,000 to 1,200 milligrams a day, which can come from calcium carbonate or calcium citrate. Several panelists point to food sources instead, such as dairy, sardines and kale, and one is weighing whether he needs a supplement at all. One panelist cautions that bone loss cannot be fixed with calcium alone, since bone also depends on collagen and other minerals, and another notes that diets and low energy intake often fall short on calcium. Vitamin D, iron and potassium are smaller ingredients in this product, and the panel mostly talks about vitamin D, with several taking about 5,000 IU a day.

See all 10 biohackers →Hide the biohackers
  • Dr. Eric Berg · Calcium · warns
    • 25 Oct 2026 · warns · YouTube ↗
      Warns that bone loss cannot be fixed with just calcium, as bone is primarily collagen with other essential minerals.
    • 2 Nov 2026 · Vitamin D · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
    • 30 Oct 2026 · Iron · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 29 Oct 2026 · Potassium · recommends · Podcast ↗
      States that people need more potassium than any other mineral, yet most people aren’t getting enough.
    • 28 Oct 2026 · Potassium · recommends · YouTube ↗
      Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
    • 25 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
    • 25 Oct 2026 · Vitamin D · recommends · X ↗
      Recommends increasing vitamin D to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Potassium · neutral · YouTube ↗
      Explains that the normal requirements for potassium are 4,700 mg every single day, and that very few people get half of that amount. They describe potassium's role in the sodium potassium pump, which is essential for cellular electricity, muscle contraction, and heart function. Deficiency can lead to tiredness, muscle cramps, heart palpitations, or rising blood pressure.
    • 25 Oct 2026 · Potassium · recommends · X ↗
      Recommends increasing potassium to restore balance and support healthy blood pressure.
    • 24 Oct 2026 · Vitamin D · neutral · YouTube ↗
      States that a lack of vitamin D can potentially cause achy bones or crashing mood.
    • 23 Oct 2026 · Vitamin D · recommends · YouTube ↗
      States that vitamin D is intimately involved in the immune system and recommends taking at least 10,000 IUs each day.
  • Siim Land · Calcium · neutral
    • 30 Sep 2026 · neutral · X ↗
      Lists dairy and sardines as sources of Calcium.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 24 Oct 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 14 Oct 2026 · Iron · neutral · Instagram ↗
      Mentions that iron is a mineral necessary for making collagen.
    • 30 Sep 2026 · Potassium · neutral · X ↗
      Lists potatoes and fruit as sources of Potassium.
    • 6 Sep 2026 · Vitamin D · recommends · Instagram ↗
      Thinks vitamin D has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · Vitamin D · neutral · X ↗
      Notes that Vitamin K2 pairs well with vitamin D by regulating calcium and bone mineralization.
    • 3 Sep 2026 · Iron · warns · YouTube ↗
      States that excess iron promotes oxidative stress and inflammation, which increases heart disease risk.
    • 26 Aug 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking vitamin D supplements with some fat to maximize its absorption, suggesting with food or a teaspoon of olive oil.
    • 23 Aug 2026 · Vitamin D · neutral · X ↗
      Notes that taking vitamin D3 with a fat-containing meal resulted in 32% higher peak blood vitamin D levels.
    • 17 Aug 2026 · Vitamin D · recommends · X ↗
      Recommends taking Vitamin D in the morning or at lunch with fat.
    • 14 Aug 2026 · neutral · X ↗
      Notes that Boron reduces calcium/magnesium loss.
    • 14 Aug 2026 · Vitamin D · neutral · X ↗
      Notes that Boron improves vitamin D.
  • Thomas DeLauer · Calcium · neutral
    • 18 Sep 2026 · neutral · Facebook ↗
      Notes that milk contains 120mg of calcium, while sardines contain 351mg, highlighting a 3x difference.
    • 28 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
    • 24 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 20 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking a massive amount of vitamin D simultaneously with an early morning massive breakfast to help reset circadian rhythms and address hyperphagia.
    • 8 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, stating that it has receptors throughout the brain and deficiency can quickly impact brain and mood.
    • 6 Oct 2026 · Vitamin D · uses · YouTube ↗
      Takes supplemental vitamin D because he is skin sensitive and from northern latitudes, limiting his UV exposure.
    • 5 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking vitamin D on non-liver days to ensure both nutrients get proper receptor access.
    • 29 Sep 2026 · Vitamin D · uses · YouTube ↗
      Takes Purity's liquid vitamin D3 with K2 because she is constantly inside during the day; D3 is for overall wellness and K2 helps the body absorb calcium properly.
    • 18 Sep 2026 · Iron · neutral · Facebook ↗
      Compares iron content in spinach (2.7mg) and beef (2.6mg), but emphasizes that beef's heme iron absorbs at about 25%, while spinach's non-heme iron absorbs at 2-8%.
    • 11 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting vitamin D, suggesting it can be obtained while walking.
    • 6 Sep 2026 · Vitamin D · recommends · Instagram ↗
      States that vitamin D is best obtained from the sun, but getting it from food definitely helps, and notes its role as a hormone influencing many cells.
    • 1 Sep 2026 · Vitamin D · recommends · Instagram ↗
      Recommends D3, suggesting a dose of 2000-4000 IU, and notes that MK-7 slowed bone loss over three years.
    • 29 Aug 2026 · Potassium · recommends · YouTube ↗
      Recommends Element's ready-to-drink sparkling electrolyte drinks as a low or zero-calorie soda replacement that provides 1,000 milligrams of sodium, 200 milligrams of potassium, and 60 milligrams of magnesium.
  • Dr. Mark Hyman · Calcium · recommends
    • 20 Aug 2026 · recommends · YouTube ↗
      Notes that calcium is in bones but is also essential for nerves, muscles, and the heart, and low levels can affect muscle function and heart rhythm.
    • 26 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Iron · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 19 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 16 Oct 2026 · Potassium · warns · Facebook ↗
      Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
    • 8 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends checking vitamin D levels and states that if they had to pick one single intervention for immune health, vitamin D would be it.
    • 7 Oct 2026 · Vitamin D · neutral · Podcast ↗
      Dr. Hyman discusses vitamin D in relation to sun exposure patterns.
    • 7 Oct 2026 · Vitamin D · recommends · YouTube ↗
      States that vitamin D supplementation can help with oxidative stress.
    • 5 Oct 2026 · Vitamin D · neutral · Podcast ↗
      Mentions vitamin D as a key nutrient for supporting immune function.
    • 5 Oct 2026 · Vitamin D · recommends · YouTube ↗
      States that vitamin D is probably the single most important intervention for immune health, recommending levels of 45 to 70 and emphasizing testing to determine the right dose.
    • 30 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that rickets, which causes terrible bone deformities, is caused by vitamin D deficiency.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D is an important nutrient for brain performance and aging, and that many people have gaps in these nutrients.
    • 31 Aug 2026 · Iron · neutral · YouTube ↗
      Notes that a woman patient had very low iron.
  • Dr. Rhonda Patrick · Calcium · neutral
    • 29 Jun 2026 · neutral · Facebook ↗
      Mentions that kale delivers calcium, a micronutrient many diets fall short on.
    • 5 Oct 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 30 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 28 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 24 Sep 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
    • 25 Aug 2026 · Vitamin D · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 28 Jul 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, noting it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity, and correcting deficiency may slow epigenetic aging.
    • 22 Jul 2026 · Vitamin D · neutral · YouTube ↗
      Uses Vitamin D3 as an example of a supplement that an AI model could track to see its impact on other metrics like glucose levels.
    • 26 Jun 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D, explaining that it regulates over 5% of the genome, including genes involved in immune defense, neurotransmitter synthesis, and longevity.
    • 23 Jun 2026 · Potassium · recommends · Facebook ↗
      Recommends getting enough potassium, noting that most people get too much sodium and not enough potassium.
    • 15 Jun 2026 · Vitamin D · neutral · Instagram ↗
      Combining omega-3s with vitamin D and exercise has an additive effect, translating to ~3 months of slowed biological aging.
    • 11 Jun 2026 · Vitamin D · neutral · Facebook ↗
      The effect got stronger when omega-3 was combined with vitamin D and resistance training, with the full stack delaying phenotypic aging by about 3.8 months.
    • 4 May 2026 · Iron · uses · YouTube ↗
      Recently found out he needed to get on an iron supplement and noticed he gets less sore in his training after taking it.
    • 22 Jan 2026 · Iron · recommends · YouTube ↗
      Advises that menstruating women should ensure they are getting enough iron.
  • Dave Asprey · Calcium · neutral
    • 16 Jun 2026 · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for calcium, which is associated with reduced bone health.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · Vitamin D · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 5 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D, noting it's actually a hormone and that most people are deficient, even those who take it, because they don't take enough.
    • 3 Sep 2026 · Vitamin D · recommends · YouTube ↗
      States that most people on the spectrum are low in vitamin D and need more of it, mentioning his own product, Vitam DAKNE, which contains real vitamin A.
    • 29 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Dave Asprey recommends Vitamin D3 with K2, explaining D3 is a hormone made from sunlight and K2 directs calcium into bones, not arteries, highlighting its low cost, widespread deficiency, and the ability to test its effectiveness.
    • 18 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Recommends Vitamin D as one of the most important supplements for overall health.
    • 12 Aug 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs because D3, A, K2, and E work together.
    • 28 Jul 2026 · Vitamin D · uses · YouTube ↗
      Mentions taking vitamin D in the morning, comparing it to the daily dosing of testosterone.
    • 24 Jun 2026 · Iron · warns · X ↗
      Warns that if a doctor diagnoses anemia, one should not assume they just need more iron, as low hemoglobin doesn't always mean low iron and the issue can sometimes be how well the body is using iron.
    • 16 Jun 2026 · Iron · neutral · Facebook ↗
      Notes that when energy intake is too low for training demand, nutrient intake often falls short, especially for iron, which is associated with impaired recovery.
    • 12 Jun 2026 · neutral · Instagram ↗
      Explains that calcium provides the raw material for bones, but it isn't a standalone input and needs a whole system to be effective.
  • Ben Greenfield · Calcium · neutral
    • 9 May 2026 · neutral · YouTube ↗
      Is considering whether he needs a calcium supplement because lead can displace calcium in bones, affecting bone strength.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 22 Oct 2026 · Potassium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises getting vitamin D levels between 60 and 100 nanograms per milliliter as a minimum step for overall health and to slow down heart disease.
    • 20 Aug 2026 · Vitamin D · uses · YouTube ↗
      Has been taking Vitamin D3 K2 for over a decade.
    • 17 Aug 2026 · Potassium · recommends · Instagram ↗
      Recommends Celtic Sea Salt's new electrolyte drink 'Hydrate' for replenishing electrolytes and trace minerals lost through sweat, noting it contains 70 naturally occurring trace minerals, magnesium, taurine, and potassium, with no added sugar, artificial colors, or synthetic ingredients.
    • 8 Aug 2026 · Vitamin D · neutral · Instagram ↗
      Notes that sunlight influences more than just vitamin D production.
    • 8 Aug 2026 · Vitamin D · recommends · YouTube ↗
      Recommends keeping vitamin D levels high, suggesting that a supplement is probably not a bad idea, especially given that many people are deficient due to spending most of their time indoors.
    • 18 Jul 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting enough vitamin D for blood pressure management.
    • 9 Jul 2026 · Vitamin D · recommends · YouTube ↗
      Recommends optimizing vitamin D levels to a serum score of around 50 to 80 nanograms per milliliter, as deficiency is linked to tinnitus volume and can assist with it.
    • 9 Jul 2026 · Iron · recommends · YouTube ↗
      Recommends testing for and replenishing iron if levels are low, as it can affect the ability to maintain or preserve muscle, especially for those on GLP-1s.
    • 7 Jun 2026 · Vitamin D · recommends · Facebook ↗
      Recommends using hormone building blocks like vitamin D for hormone optimization.
    • 29 May 2026 · Iron · neutral · Facebook ↗
      Notes that one can eat iron-rich foods or supplement with iron, but still feel exhausted if iron is not the missing piece, emphasizing that focusing on a single mineral in isolation can support a number on a lab test rather than the system itself.
  • Peter Attia · Calcium · recommends
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends calcium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 1,000 to 1,200 milligrams, which can be supplemented with calcium carbonate or calcium citrate.
    • 6 Sep 2026 · Potassium · recommends · YouTube ↗
      States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
    • 4 Jan 2026 · Vitamin D · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 16 Nov 2025 · Vitamin D · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 6 Aug 2025 · Vitamin D · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 3 Aug 2025 · Vitamin D · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · Vitamin D · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.
    • 10 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might help overcome the negative effects of phenytoin on bone health by improving calcium absorption, though he is unaware of studies on this.
    • 9 Jul 2025 · Vitamin D · recommends · YouTube ↗
      Recommends Vitamin D3 as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 800 to 1,000 IU, which can be obtained through sunlight or supplementation.
    • 6 Jul 2025 · neutral · YouTube ↗
      Explains that bone is 50 to 70% mineral, predominantly calcium, and that virtually all of the body's calcium is contained within bone, making bone important for calcium homeostasis.
    • 6 Jul 2025 · Vitamin D · neutral · YouTube ↗
      Suggests that supplementing with lots of vitamin D might overcome the negative effects of phenytoin on bone health by counteracting increased catabolism of vitamin D and subsequent decreased calcium absorption.
    • 8 Jun 2025 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D for people who tend to be vitamin D deficient, such as those living in Portland, Oregon.
    • 8 Jun 2025 · Iron · recommends · YouTube ↗
      Recommends iron supplements for women of reproductive age who are iron deficient.
    • 17 Mar 2025 · Vitamin D · neutral · Instagram ↗
      Discusses evaluating vitamin D, understanding deficiency, and optimal levels.
  • Bryan Johnson · Calcium · recommends
    • 5 Jun 2025 · recommends · YouTube ↗
      Recommends calcium as a mineral that, along with phosphorus, magnesium, and boron, is deposited to fortify the bone structure after the collagen scaffold is in place.
    • 22 Oct 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 8 Jul 2026 · Iron · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · Iron · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 3 Jul 2026 · Vitamin D · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 2 May 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 21 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 14 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 8 Apr 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 7 Apr 2026 · Vitamin D · uses · X ↗
      He takes 5000 IU of Vitamin D3 in the morning for general health.
    • 12 May 2025 · recommends · YouTube ↗
      Agrees that a little extra calcium is probably okay, especially for women, to really hit home for bone mineral density.
  • Andrew Huberman · Calcium · neutral
    • 6 Mar 2023 · neutral · Podcast ↗
      Discusses "hard water" and the role of magnesium and calcium in cardiovascular health.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 7 Aug 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for longevity.
    • 27 Jul 2026 · Potassium · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 20 Jul 2026 · Vitamin D · recommends · YouTube ↗
      States that Vitamin D is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 20 Jul 2026 · Iron · recommends · YouTube ↗
      States that Iron is one of the critical nutrients with the best evidence for cognitive function and reducing the risk of dementia.
    • 13 Jul 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning.
    • 12 Jul 2026 · Vitamin D · uses · X ↗
      He takes 5,000 IU of Vitamin D3 in the morning for overall health.
    • 6 Jul 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning.
    • 22 Jun 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning for general health.
    • 17 Jun 2026 · Vitamin D · uses · X ↗
      Takes 5000 IU of Vitamin D3 every day for longevity.
    • 6 Jun 2026 · Vitamin D · uses · X ↗
      Takes 5,000 IU of Vitamin D3 in the morning.
    • 18 May 2026 · Potassium · uses · YouTube ↗
      Uses Element, which contains potassium in the correct ratios, to ensure proper hydration and electrolyte intake for brain and body function.

RAL Summary

Members OnlyTier 4 for Regularity: Long-Term Relief

Human studies support Calcium (6 of 15 human studies showed an improvement), but there are not yet enough reviews to confirm it (29). The final check notes: The tier cites calcium as study support, but the calcium studies show plain calcium does not relieve constipation (the benefits came from calcium polycarbophil, a fiber), and calcium is only a trace nutrient here, not the product's main ingredient.

  • Emerging: not enough evidence to rank higher yet.

Where the evidence disagrees: 40 of the 76 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system

Combine with: For its intended purpose of regularity, take it with plenty of water and consider magnesium citrate or glycinate for gentle bowel support, a probiotic such as Lactobacillus or Bifidobacterium strains, and aloe or ginger for gut comfort. Separate it from medications and other supplements by 1 to 2 hours, since fiber can reduce absorption. If muscle building is the real goal, use different products: whey or plant protein (20 to 40 g per serving), creatine monohydrate (3 to 5 g daily), leucine or EAAs, vitamin D3 with K2, magnesium and omega-3s, together with resistance training and adequate calories.

Possible side effects: At much higher doses than in this product, calcium and iron supplements raised constipation in trials. No side effects were reported in reviews, since no written reviews could be read.

Supplement Facts

Total Carbohydrates 5 g · Vitamin D 6.1 mcg · Calcium 80 mg
Supplement Facts
Serving Size 1 Teaspoon(s)
Servings Per Container 32
Amount Per Serving% Daily Value
Calories20
Cholesterol5 mg
Total Carbohydrates5 g
Protein1 g
Vitamin D6.1 mcg
Calcium80 mg
Iron2.2 mg
Sodium20 mg
Potassium110 mg
Proprietary Blend6.2 g†
† Daily Value not established.

Directions: Suggested Use Take 1 rounded tsp in 4-6 oz of water or fresh pressed grape or apple juice once daily (either mid-morning or bedtime). Follow Immediately with4-6oz of water. Do not consume within 2 hours of meals and/or supplements.

Label source: NIH label database · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.