Just Ripe Nutrition PlantSulin Healthy Blood Sugar Support Supplement, Plant Sulin 4 Bottles Review

PlantSulin by Just Ripe Nutrition is an herbal dietary supplement marketed to support healthy blood sugar levels, insulin sensitivity and metabolic balance. The "4 Bottles" listing is a multipack of the same formula, usually sold as a multi-month supply. According to promotional material, the formula combines about 11 plant extracts drawn from Eastern and Western herbal traditions. Named ingredients include Astragalus root, White Mulberry leaf, Milk Thistle, Lycium (goji) berry, Solomon's Seal, Shepherd's Purse and Licorice root. It is described as vegan, non-GMO, gluten-free and stimulant-free, and it is generally described as well tolerated. The proposed mechanisms are as follows, and they come from the marketing sources. 1. **Improved insulin sensitivity.** Astragalus and Solomon's Seal are promoted as helping cells respond more efficiently to insulin. In principle, this would help glucose move from the bloodstream into tissue. 2. **Slower carbohydrate digestion.** White Mulberry leaf contains iminosugars such as 1-deoxynojirimycin (DNJ). These compounds inhibit intestinal alpha-glucosidase enzymes, which blunts the post-meal glucose spike. This is the best-supported mechanism in the published literature on mulberry leaf. 3. **Antioxidant and anti-inflammatory support.** Milk Thistle (silymarin) and Lycium polysaccharides are said to reduce the oxidative stress that high glucose places on the liver, eyes, heart and circulation. 4. **Metabolic and energy balance.** The other botanicals are positioned as supporting steadier daily energy and metabolism, without synthetic stimulants. The formula is described as "insulin-like" in its marketing. In practice it works by supporting the body's own glucose-handling pathways. It does not supply insulin. Evidence for the whole blend is limited. Some individual ingredients have small clinical studies behind them, but I found no published trial of this specific product. Licorice root can raise blood pressure and lower potassium in sensitive people. The supplement is not an approved treatment for diabetes, and the FDA does not evaluate it for efficacy. People who take meds such as insulin, meds or a med should consult a clinician before using it, because combining it with those drugs could lower blood sugar too far. Pregnant or nursing women and people with liver or blood pressure conditions should also check first. It is best used alongside diet, exercise and regular glucose monitoring.

Product Focus: Blood SugarAlso covers:HormonesHeartDigestion
Tier ⓘ
Tier 2 · Rank 21
Tier 2 · Researched. Human studies show improvement in an aging-related function or a specific goal, and the reviews agree. Rank 21 within Tier 2 for Blood Sugar; 21 of 83 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
87 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
93% of 1,300
Biohacker Mentions
10 of 10

Study, Trial or Testing Result Summary

Members Only493 human studies · 267 improved

14 of these 493 human studies gave the ingredient by drip or injection, not by mouth.

493 human studies267 improved140 no effect1,684,196 people studied

Chromium is at a full dose. Pooled trials in people with type 2 diabetes found it lowered fasting blood sugar and long-term blood sugar [1][2], and it ranked best among vitamins and minerals for fasting sugar, though certainty was low [3]. Magnesium reaches a full dose at two servings. Double-blind trials found it lowered fasting blood sugar in people with diabetes [4], although some trials saw no change [5]. Cinnamon at two servings matches a dose that lowered long-term blood sugar [6], and pooled trials agree [7]. Zinc at two servings is close to doses that lowered fasting sugar in prediabetes [8]. Alpha lipoic acid at three servings is near a dose that lowered fasting sugar in pregnancy diabetes [9]. However, the largest long trials of alpha lipoic acid found no change [10]. Banaba, gymnema, white mulberry, bitter melon, licorice, taurine, guggul, vanadium and vitamin C are present well below the doses studied, so their trial results likely do not apply here [11][12][13]. Juniper has only animal studies [14]. Pooled trials found cayenne does not change blood sugar [15]. Animal and cell studies are never counted.

See all 493 studies →Hide the studies

Review Totals and Summary

Members Only1,300 reviews · 93% positive
1,300 reviews · Google Shopping 1,300
93% positive0% neutral7% negative

I couldn't retrieve genuine customer feedback for Just Ripe Nutrition PlantSulin, so I can't responsibly extract themes from it. My searches returned only press releases, which are promotional and unreliable as a guide to customer experience. Inventing themes such as "customers praise X but complain about Y" would be fabrication. Several things are worth checking for yourself. On the Amazon listing, read the written reviews and not just the star rating. Look at whether reviewers report measurable changes in their glucose readings or A1C, as opposed to vague claims of feeling better. Check for comments about digestive side effects, the number of capsules per serving, and how long they took to notice any effect. Also check whether reviews look verified and varied. Clusters of near-identical praise can indicate incentivized reviews. It is also worth comparing the supplement facts panel against the ingredient lists in the press releases. Consult a healthcare provider before using this alongside meds. If you can share review text or a listing link, I can summarize the real themes from it.

Biohacker Summary

Members Only10 of 10 recommend it
10 of 10 biohackers on our panel recommend it

Magnesium, the main ingredient, drew comment from all ten panelists, and most of them recommend it or take it, mainly for sleep. Four of them use it themselves: one takes the glycinate form every night, one takes 400 mg of the threonate form before bed, and two get it from electrolyte drinks or cans, one of them for workout performance. Others point to the glycinate and threonate forms, and one adds that some people may do better with other types, while the rest mention muscle cramps, bone building, blood pressure, stress and a basic role during detox. Several say deficiency is hard to spot on a standard blood test, and one says it did not fix waking at night and another warns that labels can make a dose look bigger than it is. Vitamin C and zinc were the most talked about of the smaller ingredients in this product, mostly with praise for collagen, skin and immune support.

See all 10 biohackers →Hide the biohackers
  • Dr. Mark Hyman · Magnesium · uses
    • 1 Nov 2026 · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 29 Oct 2026 · Cinnamon · recommends · Instagram ↗
      Recommends adding cinnamon to coffee as a way to enjoy fall flavors without the high sugar content.
    • 21 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 14 Oct 2026 · recommends · TikTok ↗
      Recommends magnesium because it is involved in over 600 reactions in the body and up to 80% of people may have low levels that never get flagged on a standard blood test.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium as a basic supplement during detoxification to support pathways, help with constipation, and provide electrolytes.
    • 12 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends vitamin C as a basic supplement during detoxification to help with inflammation and detoxification.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Biooptimizers, which contains 10 bioavailable forms and 550 mg of elemental magnesium, to support restful sleep, restorative sleep, muscle recovery, stress resilience, and metabolic health.
    • 7 Oct 2026 · Vitamin C · neutral · Podcast ↗
      Dr. Hyman mentions vitamin C as an advanced therapy for skin repair.
    • 7 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Mentions topical vitamin C as an antioxidant that can help skin with aging.
    • 7 Oct 2026 · Zinc · uses · YouTube ↗
      Gave a patient with psoriatic arthritis a little zinc, which contributed to significant improvement in her condition.
    • 6 Oct 2026 · Vitamin C · neutral · X ↗
      Mentions that what they do when a cold comes on is not just vitamin C.
    • 5 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends ensuring adequate vitamin C intake on a regular basis for immune support, stating it's important for healthy immune function despite mixed data on its effectiveness for colds.
    • 5 Oct 2026 · Zinc · recommends · YouTube ↗
      Recommends ensuring adequate zinc intake on a regular basis for immune support, noting some data on zinc lozenges for early cold.
    • 30 Sep 2026 · uses · YouTube ↗
      Has recommended magnesium breakthrough from bioptimizers for years and now uses Magnesium Breakthrough Advanced 10 as part of his evening routine, especially during periods of travel, training, and higher stress, to support sleep, muscle recovery, and metabolic health.
  • Dave Asprey · Magnesium · neutral
    • 31 Oct 2026 · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
    • 7 Oct 2026 · Zinc · uses · YouTube ↗
      Developed a nonnano zinc sunscreen over five years, stating her skin is probably better now than it's ever been.
    • 27 Sep 2026 · recommends · Podcast ↗
      Recommends fixing sleep with 300mg of Magnesium 101 before bed if diet and exercise aren't melting stubborn belly fat.
    • 25 Sep 2026 · Taurine · neutral · Podcast ↗
      Dave Asprey explains that a 2017 study in rats found taurine pretreatment reduced several behavioral and biochemical effects of chronic unpredictable stress, but notes this does not show that taurine treats depression in humans.
    • 18 Sep 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine, a common longevity molecule, affects the sense of smell, but they do not know why it works.
    • 7 Sep 2026 · uses · Instagram ↗
      Dave Asprey says his daily routine includes magnesium as part of a carefully developed combination for longevity.
    • 5 Sep 2026 · recommends · YouTube ↗
      Recommends magnesium glycinate for sleep, stating that trials show it helps people fall asleep about 17 minutes faster and that he finds it incredibly effective.
    • 3 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium glycinate as one of the five gut-friendly, extensively researched ingredients in Kill Switch that helps with natural sleep.
    • 3 Sep 2026 · Zinc · recommends · YouTube ↗
      Emphasizes the importance of having enough zinc before trying advanced longevity strategies like peptides.
  • Dr. Eric Berg · Magnesium · neutral
    • 30 Oct 2026 · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 31 Oct 2026 · Zinc · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 28 Oct 2026 · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium, specifically magnesium glycinate, stating it is key for D3 and K2 to work and is probably more important than calcium for building bone.
    • 25 Oct 2026 · recommends · X ↗
      Recommends increasing magnesium to restore balance and support healthy blood pressure.
    • 25 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Dr. Berg states that Vitamin C helps fight biofilms and is essential for making collagen in gums, teeth, and capillaries.
    • 24 Oct 2026 · recommends · Instagram ↗
      Dr. Eric Berg suggests that magnesium could help support deeper, more restful sleep.
    • 24 Oct 2026 · recommends · YouTube ↗
      Recommends Magnesium Glycinate, noting that the combination of magnesium and glycine is helpful for connective tissue, sleep, and reducing stress.
    • 24 Oct 2026 · Zinc · recommends · YouTube ↗
      Recommends taking zinc carnosine for an ulcer or some type of gastric problem.
    • 24 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends Vitamin C as a cofactor, especially for collagen.
    • 23 Oct 2026 · recommends · Instagram ↗
      Recommends taking magnesium 90 minutes to 2 hours before bedtime to support better sleep.
    • 23 Oct 2026 · recommends · YouTube ↗
      Suggests that magnesium glycinate can help support the missing 'break pads' on the nervous system, which contribute to constant pain.
    • 23 Oct 2026 · Zinc · recommends · YouTube ↗
      Emphasizes the importance of zinc for decreasing viral replication and recommends taking 40 to 60 mg every single day.
  • Ben Greenfield · Magnesium · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Zinc · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 22 Oct 2026 · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 15 Oct 2026 · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Chromium · neutral · YouTube ↗
      Mentions chromium as a secondary ingredient in blood sugar control products, along with vanadium and bittermelon extract.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Bitter Melon · neutral · YouTube ↗
      Mentions bittermelon extract as an ingredient in blood sugar control products, along with vanadium and chromium.
    • 15 Oct 2026 · Vanadium · uses · YouTube ↗
      Put himself on a diet of chelated vanadium to help regenerate his pancreas, as vanadium was historically used for diabetes.
    • 10 Oct 2026 · Zinc · recommends · YouTube ↗
      Emphasizes that zinc sufficiency is crucial for immunity because the thymus-derived peptide thymulin, which trains lymphocytes, requires zinc to be active.
    • 24 Sep 2026 · Vitamin C · neutral · YouTube ↗
      Notes that while vitamin C has significant value, the optimal dose is a vexed question, and high doses might not always be beneficial, potentially blunting the hormetic effects of exercise.
    • 19 Sep 2026 · Zinc · recommends · YouTube ↗
      Recommends adding zinc into one's stack because it is a co-factor for enzymes involved in testosterone synthesis and sperm maturation, and zinc deficiency is a reproducible cause of low sperm count.
  • Dr. Rhonda Patrick · Magnesium · neutral
    • 29 Oct 2026 · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 16 Oct 2026 · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 12 Oct 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine depletion is a concern raised in long-term animal studies regarding Beta Alanine, though not observed in human trials, and notes that one can supplement with taurine, which is a beneficial compound.
    • 29 Sep 2026 · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 29 Sep 2026 · Zinc · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 28 Sep 2026 · Zinc · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 2 Sep 2026 · neutral · Facebook ↗
      States there is not yet strong, consistent evidence that magnesium supplementation reliably improves sleep, noting that while some meta-analyses suggest it can improve sleep quality scores, sleep efficiency, and sleep duration, individual studies are inconsistent and several have found no meaningful effect.
    • 25 Aug 2026 · Vitamin E · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 25 Aug 2026 · Vitamin C · neutral · Facebook ↗
      Lutein and zeaxanthin can also be obtained from certain multivitamins.
    • 21 Aug 2026 · Zinc · neutral · Instagram ↗
      Discusses findings from a meta-analysis on zinc supplementation, noting it improved insulin resistance, inflammation, and oxidative stress in people with diabetes or prediabetes, and explains its biological role in the pancreas.
    • 10 Aug 2026 · neutral · Facebook ↗
      States that magnesium may help modestly lower blood pressure by playing an important role in regulating vascular tone and influencing calcium signaling, with studies showing a reduction in systolic and diastolic blood pressure by 2 mmHg at a dose of around 370 mg/day for about 3 months.
    • 10 Aug 2026 · recommends · X ↗
      Recommends considering magnesium to improve mood.
    • 28 Jul 2026 · recommends · Facebook ↗
      Recommends Magnesium, stating that roughly half of Americans don’t get enough and it is a cofactor for over 300 biological processes, including DNA repair and energy production.
  • Thomas DeLauer · Magnesium · uses
    • 28 Oct 2026 · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 24 Oct 2026 · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Zinc · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 22 Oct 2026 · Taurine · recommends · YouTube ↗
      Recommends taurine, stating it raises the stress threshold, acts as a GABA and glycine receptor modulator, and protects neurons from stress, ultimately lowering cortisol release.
    • 8 Oct 2026 · recommends · Facebook ↗
      Recommends magnesium, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 8 Oct 2026 · Zinc · recommends · Facebook ↗
      Recommends zinc, noting it is a cofactor for enzymes that build neurotransmitters, and deficiency can affect mood, happiness, and motivation.
    • 6 Oct 2026 · neutral · YouTube ↗
      Notes that modern agricultural practices have led to soils depleted of trace minerals like magnesium, resulting in widespread magnesium deficiency.
    • 4 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends consuming vitamin C to aid in NADPH recycling, which is necessary for glutathione to be reused after neutralizing oxidative stress.
    • 3 Oct 2026 · Zinc · neutral · YouTube ↗
      Mentions that more zinc could be beneficial for testosterone, but it's not working on the axis that most people need help with.
    • 1 Oct 2026 · recommends · YouTube ↗
      Recommends taking some magnesium glycinate tonight to help calm down and sleep.
    • 29 Sep 2026 · Vitamin C · uses · YouTube ↗
      Takes Purity's liquid liposomal vitamin C for immune support and overall wellness, finding it easy to add to water, juice, or take straight up due to its good taste.
  • Siim Land · Magnesium · recommends
    • 25 Oct 2026 · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
    • 12 Oct 2026 · recommends · YouTube ↗
      Recommends magnesium for sleep, especially deep sleep, and suggests trying better types like Threonate, Biscinate, or Torate, referencing a study where magnesium supplementation improved deep sleep.
    • 9 Oct 2026 · Taurine · neutral · Instagram ↗
      States that taurine supports normal muscle, nerve, and heart function, and supplement trials suggest benefits for some metabolic markers, exercise performance and blood pressure.
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Magnesium for blood pressure, migraines and deficiency, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 7 Oct 2026 · Taurine · recommends · Instagram ↗
      Recommends Taurine for blood pressure and metabolic health, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 6 Oct 2026 · neutral · X ↗
      Lists Magnesium as one of 15 supplements backed by human studies.
    • 6 Oct 2026 · Taurine · neutral · X ↗
      Lists Taurine as one of 15 supplements backed by human studies.
    • 30 Sep 2026 · recommends · Instagram ↗
      States that magnesium is a fundamental mineral governing over 600 enzymes and metabolic reactions, and recommends that most people need at least 400-500 mg/d for health, with some needing up to 600 mg/d.
    • 30 Sep 2026 · neutral · X ↗
      Lists seafood and pumpkin seeds as sources of Magnesium.
    • 30 Sep 2026 · Vitamin C · neutral · X ↗
      Lists sauerkraut and fruit as sources of Vitamin C.
    • 6 Sep 2026 · recommends · Instagram ↗
      Thinks magnesium has some of the strongest evidence and is worth considering.
    • 6 Sep 2026 · Vitamin C · neutral · X ↗
      Notes that Vitamin C is one of several supplements with human evidence.
  • Andrew Huberman · Magnesium · neutral
    • 22 Oct 2026 · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 29 Oct 2026 · Zinc · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · Zinc · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 19 Oct 2026 · Zinc · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · Zinc · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · Zinc · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · Zinc · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 14 Sep 2026 · Zinc · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · Zinc · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · Zinc · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 17 Aug 2026 · Zinc · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 7 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 27 Jul 2026 · uses · YouTube ↗
      Uses Element, an electrolyte drink with sodium, magnesium, and potassium in correct ratios and no sugar, to ensure adequate hydration and electrolytes, especially when starting days fast or during physical exercise.
    • 20 Jul 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
  • Bryan Johnson · Magnesium · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 4 May 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 4 May 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 2 May 2026 · uses · X ↗
      He takes 400 mg of Double Wood Magnesium L-Threonate before bed for sleep.
    • 21 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 15 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 14 Apr 2026 · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 14 Apr 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning.
    • 8 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium L-threonate before bed for sleep.
    • 7 Apr 2026 · uses · X ↗
      He takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 5 Apr 2026 · uses · X ↗
      Takes 400 mg of magnesium threonate before bed for sleep.
    • 2 Apr 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
    • 3 Feb 2025 · Vitamin C · neutral · YouTube ↗
      Uses Vitamin C as an example of how it would be great if people knew that when they took it, it had a measurable amount and wasn't polluted, which is what Brian ensures with his products.
  • Peter Attia · Magnesium · neutral
    • 1 Jun 2026 · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Zinc · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 7 Dec 2025 · Cinnamon · uses · YouTube ↗
      Uses cinnamon in his keto mousse in the evening.
    • 15 Sep 2025 · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 9 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium as one of the 'big three' micronutrients for bone health, suggesting a daily intake of 300 to 500 milligrams as a minimum, and personally aims for about a gram of supplemental magnesium.
    • 6 Jul 2025 · recommends · YouTube ↗
      Recommends magnesium for optimizing bone mineral density, suggesting a daily intake of 300 to 500 milligrams as a minimum, but personally aims for about a gram.
    • 3 Jul 2025 · Vitamin C · stopped · YouTube ↗
      Recommends vitamin C as an important molecule for skin, noting its role as a precursor for collagen synthesis, a powerful antioxidant, and a regulator of complexion for even skin tone.
    • 29 Jun 2025 · Vitamin C · stopped · YouTube ↗
      Tried a vitamin C serum mixed with ferulic acid but stopped using it because she hated the smell. She notes that topical application of vitamin C far exceeds the levels achievable by ingestion for skin benefits.
    • 11 May 2025 · Biotin · warns · YouTube ↗
      Warns that biotin, found in many supplements, can completely obscure findings and render a non-LCMS test for estradiol and testosterone irrelevant due to interference with ELISA-based assays.
    • 15 Nov 2024 · Taurine · neutral · YouTube ↗
      Mentions that taurine supplementation in mice and other species appears to prolong life, referencing V.J. Adav's work, but notes that it is unclear if the same applies to humans.
    • 6 Sep 2024 · Zinc · neutral · YouTube ↗
      Discusses the AREDS formula, which initially included C and beta-carotene with zinc and copper, and later replaced beta-carotene with lutein and zeaxanthin, showing it could delay or reduce the conversion of mild to severe macular degeneration.
    • 6 Sep 2024 · Vitamin C · neutral · YouTube ↗
      States that vitamin C deficiency is associated with an elevated risk of cataract, but supplementation to supranormal levels has not been shown to protect against cataract formation.
    • 19 Aug 2024 · Vitamin C · recommends · YouTube ↗
      Mentions the elimination of scurvy through the work of James Lind and the eventual understanding that it was due to vitamin C, initially thought to be just citrus.

RAL Summary

Members OnlyTier 2 for Blood Sugar

Chromium at a full dose and magnesium at two servings have pooled human trials showing lower fasting blood sugar in diabetes [1][4], and 93% of 1300 reviews are positive. Note that the rules cite a 883,627-person review, which is a micronutrient review not specific to magnesium, but the tier is still supported.

Take 3 servings a day (3 capsules) to match the dose that worked in the studies.

Where the evidence disagrees: 140 of the 493 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Endocrine system, Cardiovascular system, Digestive system

Combine with: For blood sugar support, this product pairs well with berberine, chromium picolinate, alpha-lipoic acid, magnesium, and bitter melon, which complement its effects on insulin sensitivity and glucose handling. Soluble fiber such as psyllium or glucomannan can further blunt post-meal glucose spikes. If the person's actual goal is thyroid health, they should look at a separate thyroid formula containing selenium, iodine (only if appropriate), zinc, iron if deficient, vitamin D, and possibly ashwagandha, and should have TSH and free T4 levels checked. Anyone on meds or meds should consult a healthcare provider, since cinnamon and gymnema can lower blood glucose and may interact with glucose-lowering drugs.

Possible side effects: Studies reported mild stomach upset such as bloating and loose stools with mulberry leaf, and stomach side effects with high-dose vanadium, a dose far above what this product contains. No written reviews were read.

Supplement Facts

Vitamin C 50 mg · Vitamin E 7 mg · Biotin 300 mcg
Supplement Facts
Serving Size 1 Capsule
Servings Per Container 60
Amount Per Serving% Daily Value
Vitamin C50 mg
Vitamin E7 mg
Biotin300 mcg
Magnesium125 mg
Zinc8 mg
Manganese1 mg
Chromium67 mcg
Banaba Extract25 mg†
Guggul50 mg†
Bitter Melon Extract20 mg†
Licorice Extract25 mg†
Cinnamon Powder50 mg†
Gymnema Extract3 mg†
Yarrow Powder25 mg†
Cayenne Pepper Powder10 mg†
Juniper Extract13 mg†
White Mulberry Extract3 mg†
Vanadium2 mcg†
Alpha Lipoic Acid30 mg†
L-Taurine25 mg†
† Daily Value not established.

Other ingredients: Hypromellose (vegetable capsule), Rice Flour.

Directions: As a dietary supplement, take one (1) veggie capsule once a day. If desired, take two capsules daily. For best results, take 20-30 min before a meal with an 8 fl oz. glass of water or as directed by your healthcare professional.

Label source: Reverseagelab · Report a label change

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Graded November 8, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.