Thorne MediClear-SGS™ - Chocolate Review

Thorne MediClear-SGS in chocolate is an all-in-one daily powder that combines two plant-based proteins, a complete multi-vitamin and multi-mineral profile, antioxidants, and broccoli seed extract. The page describes it as a rice-and-pea protein formula offered for daily detox support in a toxic world. Each serving is 2 scoops, and the container holds 21 servings, or 42 scoops. The chocolate powder is meant to be mixed easily with water, juice, or another beverage for on-the-go nutrition, or blended into a smoothie with fruits and greens. Thorne states that the formula has more protein, detox factors, fewer carbohydrates, and added special nutrients than other daily detox alternatives, and presents it as a more affordable and more complete option. The benefits listed include powerhouse nutrition from an all-in-one daily protein and multi-vitamin and mineral supplement with added antioxidant support, daily support through chocolate or vanilla flavour options for smoothies, detox benefits that support the body's defences against modern toxic insults, and a powdered alternative to capsules that mixes with a favourite beverage. Features on the page include rice and pea proteins, which the page says are less likely to trigger allergic reactions or digestive discomfort than common protein sources. The multi-vitamin and mineral forms are described as the most absorbable, including active forms of vitamins B6, B12 and folate, and mineral chelates from Albion Laboratories. Reduced glutathione is presented as a well-absorbed antioxidant, while glycine, glutamine, taurine, vitamins A, C and E, zinc and selenium are described as building blocks the body uses to make and recycle antioxidants. Green tea and milk thistle extracts are said to support healthy liver function, and curcumin and grape seed phytosomes are said to support a healthy inflammatory response. Sulforaphane glucosinolate from broccoli seed extract is described as helping protect cells for up to 72 hours. The product is stated to be third-party tested and certified to verify that contents match the label and contain no unsafe levels of contaminants such as heavy metals, pesticides and microorganisms. Warnings on the page include a California Proposition 65 lead warning, a contraindication for individuals with hypersensitivity to any ingredient, a note that the grape seed phytosome uses soy-derived phospholipids with no soy protein, a caution for people with serious peanut allergies because the product contains pea protein, advice for pregnant people to consult a health-care practitioner, and interaction notes regarding a med with 5-MTHF folate and curcumin with certain chemotherapy agents.

Product Focus: Liver HealthAlso covers:DigestionMetabolism
Tier ⓘ
Tier 3 · Rank 3
Tier 3 · Reviewed. Strong review agreement, with limited or early support from human studies. Rank 3 within Tier 3 for Liver Health; 23 of 39 overall. Tiers run from 1, the strongest evidence, to 5. How we grade →
Evidence ⓘ
71 /100
How strongly the evidence says this product works: human studies count most, then real reviews, then our biohacker panel.
Positive Reviews
89% of 474
Biohacker Mentions
9 of 10

Study, Trial or Testing Result Summary

Members Only652 human studies · 282 improved

32 of these 652 human studies gave the ingredient by drip or injection, not by mouth.

652 human studies282 improved274 no effect1,159,764 people studied

Several ingredients have human study support for the liver at the amounts in this shake. Curcumin at 400 mg is above a studied dose; pooled trials in fatty liver found better liver scans and lower liver enzymes [1], though a 2026 pooled analysis said the benefit was not clearly meaningful [2]. Milk thistle at 250 mg is above a studied dose; pooled trials found lower liver enzymes [3] and one trial found less liver stiffness [4]. Vitamin E reaches a studied amount at the suggested servings; in non-diabetic adults with fatty liver inflammation it improved liver biopsies more than placebo [5][6]. Vitamin D at the suggested servings reduced liver fat and stiffness in one trial [7], but pooled trials found no clear change in liver enzymes [8]. Grape seed extract and folate have small positive trials [9][10]. Taurine, betaine and vanadium are present only in trace amounts, well below the studied doses [11][12]. Many vitamins and minerals in the mix, such as vitamin A and niacin, have no shown liver benefit [13][14]. Animal and cell studies are never counted.

See all 652 studies →Hide the studies

Review Totals and Summary

Members Only474 reviews · 89% positive
474 reviews · Amazon 347 · Thorne 126 · Google 1
89% positive5% neutral6% negative

Across the one store that lists it, Thorne, this product has 126 ratings (the figure given for the total is 473, but only 126 is shown for the single page), and the themes below come from the written reviews that could be read on that page. Only a handful of written reviews were visible, so everything here rests on those few comments. The page averages 4.7 stars. Taste is the most common praise for the chocolate powder. One reviewer describes it as chocolate milk style, and another says a chocolate shake delivers 25 grams of protein for breakfast and called it delicious. Another reviewer, a long-time Thorne user for years, calls this a favourite and says starting the day with a shake made from it helps them feel better. Other short comments are generic praise, such as love this, great product and very good, with little detail on specific benefits or drawbacks. On suitability, one reviewer who says they are diabetic states that the product checks the boxes for them and that a dietitian approved drinking it in place of other products on the market. The shake format is described as a convenient way to get protein at breakfast, and the protein amount is seen as good value in terms of nutrition. For complaints, the written reviews offered almost nothing negative. The main caution comes from the page's AI-generated summary, which says customers appreciate the taste, protein quality and the positive feelings it induces, while opinions on powder consistency are mixed. Popular topic tags on the page include results, quality, feel, issues, texture, consistency, amount and taste, which suggest texture and consistency come up repeatedly in the wider review set, although the visible comments do not describe them in detail. The star histogram shows very few one and two star ratings, so negative feedback appears limited on this page. No comments on price or value for money were readable. One reviewer who mentions the vanilla flavour says it goes down easily and is enjoyable served ice cold or mixed with a protein drink. That comment concerns vanilla rather than chocolate, so it is only a loose indication of how the powder is enjoyed, not a verdict on the chocolate flavour. No reviews of other forms of the product, such as gummies or capsules, were identified in the summaries, so nothing had to be left out on that basis. Overall, the readable written feedback points to a pleasant chocolate taste, convenience in a shake, and perceived protein value, with powder consistency as the main caution. Readers should weigh the small number of visible written reviews against the 126 total ratings when judging the overall experience.

Biohacker Summary

Members Only9 of 10 recommend it
9 of 10 biohackers on our panel recommend it

Curcumin is the main ingredient, and six of the ten panelists spoke about it: two recommend it, one uses it, and three are neutral. It is mostly taken for inflammation, with one panelist citing joint pain backed by human trials and another suggesting curries for immune support, and one takes it before a late night meal to avoid overeating. One panelist prefers the phytosomal form because standard curcumin is broken down quickly by the liver, and another notes that sulforaphane outperforms it as an activator of the body's Nrf2 defense pathway. No one gave a curcumin dose, and no one said they stopped or issued a caution about it. Milk thistle, also listed as a main ingredient, drew only one neutral mention, which pointed to data supporting liver health, while vitamin D, magnesium, glycine and zinc are smaller ingredients in this product that several panelists also discuss."}

See all 10 biohackers →Hide the biohackers
  • Dave Asprey · Curcumin · uses
    • 29 Oct 2026 · uses · YouTube ↗
      Says CallaCurcumin is like "mommy's little helper" and he takes it when he knows he's going to eat late at night, around 5:00 or 6:00, to avoid overeating.
    • 1 Nov 2026 · Vitamin D · uses · Facebook ↗
      Takes Vitamin DAKE from Suppgrade Labs.
    • 31 Oct 2026 · Magnesium · neutral · YouTube ↗
      Mentions magnesium in the context of sleep but states that it doesn't address the core issue of waking up during the night.
    • 25 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Suggests that vitamin D supports brain health, muscle function, and focus.
    • 25 Oct 2026 · Magnesium · recommends · Podcast ↗
      Suggests that magnesium may help slow aging, support cellular repair, and improve sleep.
    • 24 Oct 2026 · Glutathione · recommends · Facebook ↗
      Recommends detoxing with glutathione.
    • 24 Oct 2026 · Vitamin C · recommends · Facebook ↗
      Recommends taking vitamin C for better skin health.
    • 17 Oct 2026 · Magnesium · neutral · Facebook ↗
      States that magnesium can affect how the body responds to a supplement.
    • 17 Oct 2026 · Folate · neutral · Facebook ↗
      States that folate can affect how the body responds to a supplement.
    • 9 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Host Dave Asprey explains why correcting a vitamin D deficiency still makes sense for male fertility, even though supplementation did not improve overall semen parameters in a randomized trial.
    • 7 Oct 2026 · recommends · YouTube ↗
      Recommends Tetrahydro Curcuminoids, stating they lower inflammation.
    • 7 Oct 2026 · Vitamin D · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin C · uses · YouTube ↗
      States that currently, he is only taking vitamin C and vitamin D.
    • 7 Oct 2026 · Vitamin E · uses · YouTube ↗
      Dave Asprey's kids get a little bit of vitamin E every day, which helps to stabilize the bad oils they get when eating at restaurants.
  • Dr. Eric Berg · Curcumin · neutral
    • 25 Oct 2026 · neutral · Facebook ↗
      Mentions that turmeric contains curcumin, which has been studied for its effects on inflammation, joint discomfort, mood, and blood sugar.
    • 2 Nov 2026 · Vitamin D · warns · Facebook ↗
      Dr. Berg warns that the recommended daily intake for vitamin D is based on a massive error and that the actual necessary amount is closer to 8,895 IU, with millions remaining deficient.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends getting vitamin D levels tested to ensure they are between 50 and 70, as vitamin D is intimately involved in regulating prostate size.
    • 31 Oct 2026 · Zinc · recommends · YouTube ↗
      Recommends ensuring sufficient zinc intake because the prostate needs enough zinc for the conversion from testosterone to DHT to be smooth and optimized.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking at least 10,000 IUs of vitamin D3 every single day in the winter, stating it is the most important vitamin to lower cancer risk.
    • 30 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends vitamin D to support the immune system, aiming for blood levels between 80 to 100 ng per ml.
    • 30 Oct 2026 · Magnesium · neutral · Instagram ↗
      Dr. Eric Berg states that magnesium supports energy, muscle function, and sleep, and that most of it is stored inside cells, making deficiencies harder to detect with a standard blood test.
    • 30 Oct 2026 · Sulforaphane · recommends · YouTube ↗
      Recommends adding sulforaphane, a phytonutrient found in broccoli sprouts or radish sprouts, to the diet for its studied effects against cancer.
    • 30 Oct 2026 · Iron · neutral · YouTube ↗
      Identifies iron as the Achilles' heel of cancer, as it is needed for its DNA to replicate.
    • 29 Oct 2026 · Potassium · recommends · Podcast ↗
      States that people need more potassium than any other mineral, yet most people aren’t getting enough.
    • 28 Oct 2026 · Magnesium · neutral · YouTube ↗
      Notes that magnesium could also be a factor in preventing muscle cramps.
    • 28 Oct 2026 · Potassium · recommends · YouTube ↗
      Explains that potassium is essential for peristalsis, the pumping action through the colon, and without it, things can sit there, leading to constipation.
    • 26 Oct 2026 · Vitamin C · neutral · YouTube ↗
      Mentions that lemon is loaded with vitamin C, and when combined with coffee, vitamin C significantly increases the bioavailability of antioxidants in the coffee.
    • 25 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Recommends taking no less than 10,000 IU's of vitamin D3 for osteoporosis, alongside magnesium and K2.
  • Thomas DeLauer · Milk Thistle · neutral
    • 16 Oct 2026 · neutral · YouTube ↗
      Notes that Dose Daily contains organic milk thistle, highlighting its significant data supporting liver health benefits.
    • 28 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's cans which contain 30 milligram magnesium, finding that electrolytes help his workout performance.
    • 28 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's cans which contain 100 milligram potassium, finding that electrolytes help his workout performance.
    • 27 Oct 2026 · Glycine · neutral · YouTube ↗
      Explains that glycine is critical for collagen synthesis, which supports the intestinal wall, and deficiency can slow down the repair process.
    • 26 Oct 2026 · Glycine · recommends · YouTube ↗
      Explains that the body needs roughly 10g more of glycine per day than a typical modern diet provides, and that this deficit can lead to issues with creatine production, connective tissue repair, and sleep. He recommends increasing glycine intake.
    • 26 Oct 2026 · Vitamin C · recommends · YouTube ↗
      Recommends taking vitamin C along with collagen about an hour before a workout for connective tissue benefits.
    • 24 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses Element's 30 mg magnesium cans first thing in the morning to prime his day and help with workout performance.
    • 24 Oct 2026 · Potassium · uses · YouTube ↗
      Uses Element's 100 mg potassium cans first thing in the morning to prime his day and help with workout performance.
    • 23 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends magnesium around the time one would normally break a fast to calm the brain and dull feelings of conditioned hunger.
    • 23 Oct 2026 · Vitamin C · uses · YouTube ↗
      Uses vitamin C as part of their immunity duo, stating it is important for boosting the immune system, especially during cold and flu season.
    • 23 Oct 2026 · Zinc · uses · YouTube ↗
      Adds zinc to their immunity duo because it helps them absorb vitamin C, considering the two together a fantastic combination for fall and winter.
    • 23 Oct 2026 · Vitamin D · uses · YouTube ↗
      Uses vitamin D3 in the fall and winter months when getting less sun, as it's important to supplement it then.
    • 22 Oct 2026 · Taurine · recommends · YouTube ↗
      Recommends taurine, stating it raises the stress threshold, acts as a GABA and glycine receptor modulator, and protects neurons from stress, ultimately lowering cortisol release.
    • 21 Oct 2026 · Sulforaphane · recommends · YouTube ↗
      Recommends rotating thymoquinone with other NRF2 activators like sulforaphane instead of stacking it daily to maintain sensitivity and preserve intensity.
  • Siim Land · Curcumin · recommends
    • 7 Oct 2026 · recommends · Instagram ↗
      Recommends Curcumin for joint pain and inflammation, based primarily on human research, especially randomized controlled trials showing measurable benefits.
    • 31 Oct 2026 · Glycine · recommends · Instagram ↗
      Suggests that a higher glycine to methionine ratio appears to preferentially target visceral fat and improve insulin sensitivity.
    • 31 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Advises against taking vitamin D in the morning with other supplements because it is fat soluble and requires dietary fat for better absorption.
    • 29 Oct 2026 · Glycine · recommends · Instagram ↗
      Recommends pairing NAC with glycine to support antioxidant activity in your sleep.
    • 29 Oct 2026 · Vitamin D · recommends · Instagram ↗
      Recommends taking Vitamin D with fat for better absorption.
    • 29 Oct 2026 · Vitamin C · recommends · Instagram ↗
      Recommends taking vitamin C with collagen to support joint collagen synthesis.
    • 26 Oct 2026 · Glycine · recommends · YouTube ↗
      Believes glycine is the best longevity supplement and encourages viewers to learn more about its longevity benefits.
    • 25 Oct 2026 · Glycine · recommends · Instagram ↗
      States that Glycine can be a useful addition for some people for sleep.
    • 25 Oct 2026 · Magnesium · recommends · Instagram ↗
      States that Magnesium can be a useful addition for some people for sleep.
    • 24 Oct 2026 · Vitamin D · neutral · Instagram ↗
      States that Vitamin D connects biology to light and that UVB reaching the skin enables its production.
    • 21 Oct 2026 · Glycine · uses · YouTube ↗
      Increased his glycine supplementation to 10g a day, noting that it balances methionine and improves blood sugar and glycation.
    • 19 Oct 2026 · Glycine · uses · YouTube ↗
      Personally uses glycine for its health benefits, including glutathione, blood sugar glycation, and potentially sleep, and notes that it appears to have some autophagy benefits by increasing autophagy through its role in methionine metabolism.
    • 14 Oct 2026 · Glycine · neutral · Instagram ↗
      Notes that glycine is one of the most important building blocks for collagen synthesis, making up 30% of collagen, and that 12g of glycine a day is needed for collagen turnover.
    • 14 Oct 2026 · Vitamin C · neutral · Instagram ↗
      States that vitamin C is needed for initiating collagen synthesis and that higher vitamin C intake appears to increase vitamin C content in the skin.
  • Dr. Mark Hyman · Curcumin · recommends
    • 5 Oct 2026 · recommends · YouTube ↗
      States that curcumin is great for immune support and is anti-inflammatory, suggesting making curries.
    • 1 Nov 2026 · Magnesium · uses · Facebook ↗
      Recommends considering magnesium glycinate before bed for nervous system support, deeper sleep quality, and to help the body transition into rest, and states that they take it every night.
    • 28 Oct 2026 · Glutathione · recommends · YouTube ↗
      Recommends Rosen Nutrition Liposomal Glutathione to support immunity through colder months, noting it helps maintain healthy immune cell function, supports natural detoxification, and neutralizes free radicals.
    • 26 Oct 2026 · Vitamin D · recommends · Facebook ↗
      Recommends Vitamin D for health, stating that amazing things happen when patients' vitamin D statuses reach optimal levels.
    • 21 Oct 2026 · Magnesium · recommends · YouTube ↗
      Recommends Magnesium Breakthrough Advanced 10 from Bioptimizers for restful sleep, muscle recovery, stress resilience, and metabolic health, especially during stressful times of the year.
    • 21 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Mentions vitamin D as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Iron · neutral · YouTube ↗
      Mentions iron as an existing biomarker that plays a role in mental health, which Function Health includes in their measurements.
    • 21 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that taking folate can lower homocysteine levels, which has shown health benefits and physical improvements in brain scans in clinical trials.
    • 19 Oct 2026 · Glutathione · neutral · YouTube ↗
      Mentions that sulforaphane helps the body make glutathione, an amazing nutrient that helps the body get rid of toxins.
    • 19 Oct 2026 · Vitamin D · neutral · YouTube ↗
      Notes that vitamin D plays a role in immune function.
    • 19 Oct 2026 · Folate · neutral · YouTube ↗
      Notes that some people may need a little bit extra folate with a supplement.
    • 19 Oct 2026 · Sulforaphane · neutral · YouTube ↗
      Notes that sulforaphane, found in cruciferous vegetables, is excellent for general detoxification, helps the body produce glutathione, and assists with estrogen metabolism.
    • 19 Oct 2026 · Vitamin A · neutral · YouTube ↗
      Mentions that vitamin A levels can be looked at to get a deep sense of what's happening with nutrient levels.
    • 16 Oct 2026 · Potassium · warns · Facebook ↗
      Warns that potassium bromate, a dough conditioner banned in the EU, UK, and Canada, is still allowed in U.S. bread.
  • Dr. Rhonda Patrick · Curcumin · neutral
    • 5 Aug 2026 · neutral · Facebook ↗
      Curcumin may be one of the most powerful naturally occurring dietary compounds for lowering age-related inflammation. The phytosomal form is preferred because standard curcumin is rapidly broken down by the liver, while phytosomal delivery makes it far more bioavailable.
    • 29 Oct 2026 · Magnesium · neutral · Facebook ↗
      Magnesium supplementation has lowered blood pressure in randomized controlled trials. An analysis of 34 trials involving over 2,000 participants found modest reductions in both systolic and diastolic pressure, with a median dose of 368 mg/day.
    • 21 Oct 2026 · Sulforaphane · uses · YouTube ↗
      Takes sulforaphane every day to activate enzymes that make plastic-associated chemicals like BPA and phthalates water soluble for excretion, noting it's the biggest dietary activator of the NRF2 detox system.
    • 16 Oct 2026 · Magnesium · warns · Facebook ↗
      Warns that some magnesium supplements make the dose look much larger than it really is and that labels can fool people.
    • 12 Oct 2026 · Taurine · neutral · YouTube ↗
      Mentions that taurine depletion is a concern raised in long-term animal studies regarding Beta Alanine, though not observed in human trials, and notes that one can supplement with taurine, which is a beneficial compound.
    • 5 Oct 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D supplementation was linked to a 40% lower risk of dementia in an observational study of more than 12,000 older adults.
    • 30 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Mentions that vitamin D also plays a role in maintaining muscle mass.
    • 29 Sep 2026 · Magnesium · recommends · YouTube ↗
      Mentions magnesium as an important nutrient component for testosterone.
    • 29 Sep 2026 · Zinc · recommends · YouTube ↗
      Notes that not getting enough zinc can affect testosterone, as zinc is very important for testosterone synthesis.
    • 28 Sep 2026 · Magnesium · warns · YouTube ↗
      Warns that some supplement companies mislead consumers by listing the total compound weight of magnesium citrate as the elemental magnesium dose, when the actual elemental magnesium content is much lower, potentially around 44-66 milligrams.
    • 28 Sep 2026 · Vitamin D · recommends · YouTube ↗
      Recommends ensuring adequate vitamin D intake for men's sperm health.
    • 28 Sep 2026 · Zinc · recommends · YouTube ↗
      Recommends men take a 30 milligram zinc supplement for sperm health when preparing for IVF.
    • 28 Sep 2026 · Folate · recommends · YouTube ↗
      Recommends ensuring adequate methyl folate intake, ideally through a prenatal vitamin, for women preparing for IVF.
    • 24 Sep 2026 · Vitamin D · neutral · Facebook ↗
      Vitamin D and strength training alone did not, but adding them strengthened the effect on one clock, with the full combination slowing that measure by ~3.8 months.
  • Ben Greenfield · Curcumin · neutral
    • 13 Jun 2026 · neutral · Facebook ↗
      Mentions curcumin as another Nrf2 activator, but notes that sulforaphane outperforms it.
    • 29 Oct 2026 · Glutathione · uses · YouTube ↗
      Will do glutathione for some patients after surgery.
    • 29 Oct 2026 · Magnesium · uses · YouTube ↗
      Uses magnesium during surgery because it is neuroprotective.
    • 29 Oct 2026 · Zinc · warns · YouTube ↗
      Ben Greenfield's formulation includes 30 grams of zinc a day, taken for one week before surgery and two weeks after, as it is an important cofactor for wound healing.
    • 29 Oct 2026 · Vitamin E · neutral · YouTube ↗
      Mentions a recent study showing no significant increase in bleeding for patients on Vitamin E supplementation during open heart surgery, which was interesting for him to learn.
    • 29 Oct 2026 · Vitamin C · recommends · YouTube ↗
      States that vitamin C is extremely important for collagen turnover and cites orthopedic data showing that 500 mg to 1 g of vitamin C can reduce the rate of complex regional pain in total knee replacements and wrist fractures.
    • 29 Oct 2026 · Vitamin D · recommends · YouTube ↗
      Notes that Vitamin D is actually a hormone and recommends patients aim for levels around 40 to 50, or even 60 for fracture healing, for optimal healing, as opposed to just above 20 which is considered normal.
    • 22 Oct 2026 · Magnesium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 22 Oct 2026 · Potassium · uses · YouTube ↗
      Says he is drinking LMNT, which contains sodium, potassium, and magnesium, and states that he actually drinks this stuff.
    • 21 Oct 2026 · Vitamin A · neutral · Instagram ↗
      Notes that Vitamin A is a fat-soluble vitamin that supports healthy skin cell turnover.
    • 15 Oct 2026 · Magnesium · recommends · Podcast ↗
      Mentions magnesium as part of a bare-minimum protocol.
    • 15 Oct 2026 · Magnesium · recommends · YouTube ↗
      Advises getting red blood cell magnesium levels to the high end of the range as a minimum step for overall health and to slow down heart disease.
    • 15 Oct 2026 · Vitamin C · recommends · Podcast ↗
      Mentions vitamin C as part of a bare-minimum protocol.
    • 15 Oct 2026 · Vitamin D · recommends · Podcast ↗
      Mentions vitamin D as part of a bare-minimum protocol.
  • Andrew Huberman · Curcumin · neutral
    • 13 Apr 2026 · neutral · Podcast ↗
      Discusses curcumin as a supplement for prenatal care and sperm health.
    • 29 Oct 2026 · Zinc · uses · YouTube ↗
      Zinc carnosine to support and improve the lining of your gut.
    • 26 Oct 2026 · Zinc · uses · YouTube ↗
      Notes that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 22 Oct 2026 · Magnesium · neutral · Podcast ↗
      Discusses Magnesium Threonate as a tool for falling asleep.
    • 19 Oct 2026 · Zinc · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut.
    • 12 Oct 2026 · Zinc · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 28 Sep 2026 · Zinc · uses · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of the gut, and he was already taking some of these ingredients separately.
    • 21 Sep 2026 · Zinc · uses · YouTube ↗
      States that AG1 Pro includes zinc carnosine, which he was already taking separately, to support and improve the lining of the gut.
    • 21 Sep 2026 · Vitamin D · neutral · YouTube ↗
      Notes that most people are probably deficient in vitamin D and benefit from supplementing, but there's no point in doing it unless you're deficient for most things.
    • 14 Sep 2026 · Zinc · uses · YouTube ↗
      Personally takes zinc carnosine, which is included in AG1 Pro to support and improve the lining of the gut.
    • 31 Aug 2026 · Zinc · uses · YouTube ↗
      AG1 Pro has zinc carnosine to support and improve the lining of your gut. Some of these ingredients I personally was already taking separate from the AG1 formula.
    • 24 Aug 2026 · Zinc · recommends · YouTube ↗
      States that AG1 Pro contains zinc carnosine to support and improve the lining of your gut.
    • 17 Aug 2026 · Zinc · uses · YouTube ↗
      Uses AG1 Pro, which contains zinc carnosine to support and improve the lining of the gut.
    • 13 Aug 2026 · Glutathione · neutral · YouTube ↗
      Dr. Gottfried looks at glutathione in nutritional testing, considering it an important lever.
  • Bryan Johnson · Vitamin D · uses
    • 22 Oct 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 22 Oct 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 22 Oct 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 15 Aug 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for general health.
    • 15 Aug 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 15 Aug 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium L-Threonate before bed for sleep.
    • 8 Jul 2026 · Iron · stopped · YouTube ↗
      Has had low iron for 11 years and despite eating meat and trying all forms of iron supplementation at different times and sequences, none of it worked to raise his iron or ferritin levels.
    • 7 Jul 2026 · Iron · uses · X ↗
      Had low iron for 11 years, with ferritin averaging 38 ng/mL, and has finally boosted it back to healthy levels.
    • 3 Jul 2026 · neutral · X ↗
      Mentions that the sunlight assessment claims low vitamin D levels cause the immune system to misfire, and notes that their vitamin D has been measured.
    • 4 May 2026 · uses · X ↗
      Takes 5000 IU of Vitamin D3 in the morning for longevity.
    • 4 May 2026 · Glycine · uses · X ↗
      Takes 2 grams of Glycine before bed for sleep.
    • 4 May 2026 · Magnesium · uses · X ↗
      Takes 400 mg of Magnesium Threonate before bed for sleep.
    • 4 May 2026 · Boron · uses · X ↗
      Takes 2 mg of Boron in the morning for longevity.
    • 4 May 2026 · Zinc · uses · X ↗
      Takes 15 mg of Zinc in the morning for longevity.
  • Peter Attia · Potassium · recommends
    • 6 Sep 2026 · recommends · YouTube ↗
      States there is some evidence that increasing dietary potassium through potassium-rich foods like bananas and potatoes, rather than supplements, can lower blood pressure.
    • 1 Jun 2026 · Magnesium · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 1 Jun 2026 · Glycine · neutral · Podcast ↗
      Peter reviews the evidence for select off-label medications and supplements commonly used for sleep, including glycine, magnesium, ashwagandha, and phosphatidylserine.
    • 4 Jan 2026 · Magnesium · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 4 Jan 2026 · Vitamin D · uses · YouTube ↗
      Lists vitamin D as one of her staple supplements.
    • 4 Jan 2026 · Zinc · recommends · YouTube ↗
      Suggests that zinc and magnesium could potentially help with vasodilation and sleep, particularly for women experiencing severe symptoms in the luteal phase.
    • 16 Nov 2025 · Vitamin D · neutral · YouTube ↗
      Notes that several studies show patients taking vitamin D can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 16 Nov 2025 · Selenium · neutral · YouTube ↗
      Notes that several studies show patients taking selenium can reduce TPO levels and prolong the honeymoon period of Hashimoto's disease.
    • 15 Sep 2025 · Magnesium · recommends · Podcast ↗
      Peter discusses electrolytes and fiber and the ketogenic diet, specifically preventing magnesium loss.
    • 6 Aug 2025 · Vitamin D · neutral · YouTube ↗
      States that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin D for both sexes.
    • 6 Aug 2025 · Vitamin A · neutral · YouTube ↗
      Notes that in mouse studies, there was a combined effect of alpha ketoglutarate with vitamin A for male mice.
    • 3 Aug 2025 · Vitamin D · neutral · YouTube ↗
      Uses vitamin D as an example of how people might dismiss its efficacy due to failed clinical trials that didn't adjust the dose or measure levels.
    • 20 Jul 2025 · Glycine · neutral · YouTube ↗
      Mentions that they also see positive effects of glycine, among other things.
    • 20 Jul 2025 · Vitamin D · neutral · YouTube ↗
      In mouse studies, Peter Attia's team found a combined effect of AKG with Vitamin D for both sexes.

RAL Summary

Members OnlyTier 3 for Liver Health

Tier 3 fits: 484 reviews are 89% positive, and full-dose ingredients such as vitamin E, curcumin and milk thistle have human trials showing liver improvement [5][1][3].

Take 3 servings a day (6 scoops) to match the dose that worked in the studies.

Where the evidence disagrees: 274 of the 652 human studies found no effect.

More Details

Members OnlyBody systems · Combine with · Possible side effects

Body systems: Digestive system, Liver, Metabolic system

Combine with: For its detox and liver purpose, MediClear-SGS pairs well with milk thistle (silymarin), N-acetylcysteine or glutathione, and extra sulforaphane or DIM to support Phase II conjugation. Fiber such as psyllium or PGX and probiotics can help bind and eliminate processed toxins. If the real goal is blood sugar support, consider stacking it with berberine, alpha-lipoic acid, chromium picolinate, magnesium, and Ceylon cinnamon, and discuss any glucose-lowering supplements with a clinician, especially if taking meds.

Possible side effects: High-dose green tea extract, sustained-release niacin and very absorbable curcumin products were linked to raised liver enzymes in studies, at doses far above this product's amounts. Reviews mention mixed opinions on powder texture and consistency.

Supplement Facts

Includes 5 g Added Sugars 0 · Vitamin A 1.5 mg · Vitamin C 300 mg
Supplement Facts
Serving Size Two Scoops (51.5 g)
Servings Per Container 21
Amount Per Serving% Daily Value
Calories170
Total Fat3.5 g
Saturated Fat2 g
Total Carbohydrate9 g
Dietary Fiber2 g
Total Sugars5 g
Includes 5 g Added Sugars
Protein20 g
Vitamin A1.5 mg
Vitamin C300 mg
Vitamin D10 mcg
Vitamin E80.6 mg
Thiamin12 mg
Riboflavin5 mg
Niacin38 mg
Vitamin B610 mg
Folate500 mcg DFE
Vitamin B1250 mcg
Biotin150 mcg
Pantothenic Acid50 mg
Choline11 mg
Calcium300 mg
Iron7 mg
Magnesium150 mg
Zinc10 mg
Selenium70 mcg
Manganese1.5 mg
Chromium100 mcg
Molybdenum50 mcg
Sodium360 mg
Potassium100 mg
Proprietary Blend25 g†
Glycine1.65 g†
Medium Chain Triglycerides (MCTs)1.5 g†
L-Glutamine500 mg†
L-Lysine500 mg†
Curcumin Phytosome††††400 mg†
Milk Thistle Extract250 mg†
Taurine110 mg†
Methyl Sulfonyl Methane (MSM)100 mg†
Grape Seed Phytosome††††50 mg†
Green Tea Phytosome††††50 mg†
Betaine Anhydrous50 mg†
Sulforaphane Glucosinolate30 mg†
Glutathione30 mg†
Boron100 mcg†
Lutein60 mcg†
Vanadium50 mcg†
† Daily Value not established.

Other ingredients: Cocoa, Cane Sugar, Flavor, Xanthan Gum, Yeast Extract, Monk Fruit extract, Silicon Dioxide.

Directions: For adults and children 12 or more years of age. Mix one serving (two scoops) with at least 10 ounces of cold water, juice, rice milk, or nut milk or as recommended by your health-care practitioner.

Label source: Reverseagelab · Report a label change

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Graded November 6, 2026 by the Reverse Age Lab evidence engine, from human studies, real reviews and our biohacker panel. How we grade. Is this medical advice? No. Rala organizes the published evidence; go over any change with your doctor, especially if you take meds.