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Life Extension supplements, graded by the human studies

We graded 27 Life Extension products against the human studies of their ingredients, the dose on each label and what buyers say in their reviews. Each grade belongs to the product and the goal it was graded for: we do not grade how Life Extension makes, tests or sells its products, and we sell no supplements. Educational, not medical advice.

Products graded
27
Goals graded for
17
Top-ranked for their goal
Tier 1, Studied
Tier 2, Researched
Tier 3, Reviewed
Tier 4, Emerging
Tier 5, Not Endorsed
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The Life Extension products we graded

Members27 products, A to Z
Life Extension 5-LOX Inhibitor with AprèsFlex® bottle
5-LOX Inhibitor with AprèsFlex®
graded for Joints and Mobility · AprèsFlex® (Boswellia serrata) extract (gum resin) [std. to 20% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA)] 100 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Black Cumin Seed Oil bottle
Black Cumin Seed Oil
graded for Healthy Aging · Black Cumin organic nigella oil (seed) 500 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension CoQ10 + PQQ bottle
CoQ10 + PQQ
graded for Healthy Aging · Ubiquinol (as Kaneka Ubiquinol™) 100 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Enhanced Sex for Men Prelox bottle
Enhanced Sex for Men Prelox
graded for Sexual Health for Men · Prelox® Proprietary Blend 720 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Enhanced Zinc Lozenges, 18.75 mg bottle
Enhanced Zinc Lozenges, 18.75 mg
graded for Immune Health · Calories 20 per serving · reviews positive · a month
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Life Extension European Milk Thistle bottle
European Milk Thistle
graded for Liver Health · Milk Thistle (Silybum marianum) Extract (seed) [std. to 80% Silymarin (600 mg) by UV, 30% Silibinins (225 mg), and 8% Isosilybin A and Isosilybin B (60 mg)] 750 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Glycine and N-Acetyl-L-Cysteine bottle
Glycine and N-Acetyl-L-Cysteine
graded for Healthy Aging · N-Acetyl-L-Cysteine (free-form) 1800 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Hair, Skin & Nails Collagen Plus Formula bottle
Hair, Skin & Nails Collagen Plus Formula
graded for Hair Growth · Niacin (as niacinamide) 18 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension N-Acetyl-L-Cysteine 600 mg bottle
N-Acetyl-L-Cysteine 600 mg
graded for Lungs and Breathing · N-acetyl-L-cysteine 600 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension NAD+ Cell Regenerator bottle
NAD+ Cell Regenerator
graded for Healthy Aging · NIAGEN® Nicotinamide Riboside Chloride 300 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Neuro-Mag Magnesium L-Threonate bottle
Neuro-Mag Magnesium L-Threonate
graded for Focus and Memory · Magnesium (from 2000 mg Magtein® magnesium L-threonate) 144 mg per serving · a month
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Life Extension No Flush Niacin bottle
No Flush Niacin
graded for Cholesterol · Niacin (from 800 mg of inositol hexanicotinate) 640 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Optimized Folate L-Methylfolate 1700 mcg DFE bottle
Optimized Folate L-Methylfolate 1700 mcg DFE
graded for Healthy Aging · Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] 1700 mcg DFE per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Optimized Saffron bottle
Optimized Saffron
graded for Mood · Satiereal® saffron extract (stigma) [std. to 0.34% safranal] 78 mg per serving · reviews positive · a month
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Life Extension Optimized Saffron with Satiereal bottle
Optimized Saffron with Satiereal
graded for Weight and Metabolism for Women · Satiereal® saffron extract (stigma) [std. to 0.34% safranal] 78 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Pregnenolone 50mg bottle
Pregnenolone 50mg
graded for Adrenal Support · Pregnenolone 50 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Prelox Enhanced Sex for Men bottle
Prelox Enhanced Sex for Men
graded for Sexual Health for Men · Prelox® Proprietary Blend (L-Arginine HCl, Aspartic Acid, Pycnogenol® Dried French Maritime Pine extract (bark)) 720 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Prolox Enhanced Sex bottle
Prolox Enhanced Sex
graded for Sexual Health for Men · Prelox® Proprietary Blend 720 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Pterostilbene bottle
Pterostilbene
graded for Healthy Aging · trans-Pterostilbene (from pTeroPure®) 50 mg per serving
Tier+ Add to Protocol
Life Extension Sensoril Ashwagandha 125 mg bottle
Sensoril Ashwagandha 125 mg
graded for Stress and Calm · Sensoril® Ashwagandha extract (root and leaf) [std. to 32% oligosaccharides, 10% withanolide glycoside conjugates] 125 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Silymarin bottle
Silymarin
graded for Liver Health · Silymarin [from milk thistle extract (seed)] 100 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Skin Restoring Ceramides bottle
Skin Restoring Ceramides
graded for Younger-Looking Skin for Women · Ceratiq® wheat (Triticum vulgare) oil extract (providing glycolipids, phytoceramides and glycosylceramides) 350 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Super Bio-Curcumin bottle
Super Bio-Curcumin
graded for Healthy Aging · BCM-95® Bio-Curcumin® turmeric 25:1 extract (root) [std. to 95% Total Curcuminoids Complex with Essential Oils of Turmeric Rhizome by HPLC (380 mg)] 400 mg per serving · reviews positive · a month
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Life Extension Super Miraforte with Standardized Lignans bottle
Super Miraforte with Standardized Lignans
graded for Hormone Balance for Men · Bioperine® piperine [from black pepper extract (fruit)] 7.5 mg per serving · reviews positive
Tier+ Add to Protocol
Life Extension Taurine bottle
Taurine
graded for Gallbladder and Fat Digestion · Taurine 1000 mg per serving · reviews positive · a month
Tier+ Add to Protocol
Life Extension Two-Per-Day Multivitamin bottle
Two-Per-Day Multivitamin
graded for Energy · Magnesium (as magnesium oxide) 100 mg per serving · a month
Tier+ Add to Protocol
Life Extension Vitamin B12 Methylcobalamin bottle
Vitamin B12 Methylcobalamin
graded for Healthy Aging · Vitamin B12 (as methylcobalamin) 5 mg per serving · reviews positive · a month
Tier+ Add to Protocol

Members see each product's tier, its reviews and why. Start My 7-Day Free Trial →

What Life Extension products were graded for

Each goal links to its page, with every product graded for it
GoalLife Extension products
Healthy Aging8
Sexual Health for Men3
Liver Health2
Adrenal Support1
Cholesterol1
Energy1
Focus and Memory1
Gallbladder and Fat Digestion1
Hair Growth1
Hormone Balance for Men1
Immune Health1
Joints and Mobility1
Lungs and Breathing1
Mood1
Stress and Calm1
Weight and Metabolism for Women1
Younger-Looking Skin for Women1

Read more

Our articles on these goals

Questions people ask

Members

Is Life Extension a good brand?

Answer for members.

Which Life Extension products have the strongest evidence?

Answer for members.

How does Reverse Age Lab grade Life Extension products?

Answer for members.

Can I take Life Extension supplements with my meds?

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Educational, not medical advice. Grades come from human studies on PubMed, the dose on each label, store reviews we read ourselves and our biohacker panel, and are updated as new studies arrive. Life Extension is a trademark of its owner; Reverse Age Lab is not affiliated with it and sells no supplements. How we grade →