The evidence base

By the Numbers

What Rala read before it built your protocol.

Reverse Age Lab sells no supplements. Rala, our patent pending AI, reads the human studies, the real reviews and what the top 10 biohackers actually say, then consolidates all of it into one daily protocol built from your own health profile. Here is how much that is.

Sells no supplements
Reads studies, reviews & biohackers
Consolidated into your protocol

Evidence · Layer one

Studies, Trials & Reviews

The research on the ingredient, the reviews on the bottle

Rala searches PubMed, the National Library of Medicine's index of medical research, at the ingredient level, so a study on calcium AKG applies to every product that contains it. Then it reads the consumer reviews on Amazon, iHerb, Walmart and the brand's own site for the product itself. A study says what an ingredient can do; the reviews say whether this bottle delivers it. Animal and cell studies are noted but never count as proof.

23.8 million

Studies in humans

Not mice, not cells. People. 1.04 million of them are clinical trials, the strongest single kind of evidence.

Source · PubMed, US National Library of Medicine

Supporting research

223,108

Human studies on supplements and nutrients

Dietary supplements, vitamins, micronutrients, plant extracts and probiotics.

43,624

Supplement trials, systematic reviews and meta-analyses

The top of the evidence pyramid for supplements.

Market & real-world context

121,959

Supplement products on the US market

Every one of them can be graded. Counted from the NIH Dietary Supplement Label Database; the FDA puts the market at about 100,000 products.

60 million+

Consumer reviews on those products, estimated

Across Amazon, iHerb, Walmart and brand sites. A low estimate: the product count times the 519 reviews a typical product carries.

Evidence · Layer two

Top 10 Biohackers

Everything they have said, read and filed

A fixed panel of the top 10 biohackers, read in full: their videos, podcasts, sites and posts. Rala extracts every statement about a supplement, a practice or a goal and files it by topic with the dose, timing and stance. Weekly sweeps pick up everything new.

The panel
10
Top 10 biohackers, read in full
A fixed panel. No cherry picking.
Read across
51,779
Videos, episodes, posts and pages read
Across YouTube, podcasts, X, Instagram, Facebook, TikTok and their own sites.
Producing
443,289
Statements extracted
Who said it, about what, for which goal, at what dose and timing.
Filed into
60,981
Topics tracked
19,264 ingredients, 18,589 methods and practices, 12,278 products, 8,370 goals and conditions, 2,480 protocols
Resulting in
96,699
Biohacker positions on record
One biohacker's stance on one topic, with the quotes behind it.

Where the library comes from

A breakdown of the sources Rala reads.

YouTube videos16,167
Podcast episodes12,234
X posts5,638
Instagram posts and videos5,228
Web pages4,956
Facebook posts3,956
TikTok videos3,587

Refreshed by weekly sweeps.

How it becomes a protocol

Research
Reviews
Biohacker intelligence
Your health profile
Your personalized protocol

We consolidate all of this to build your protocol.

Enter your health profile, goals, supplements, medications and blood work, and Rala turns everything above into one daily protocol: what to take, when, and why, with the conflicts, redundancies and timing worked out. It re-derives whenever something about you changes.

Build My Protocol – 7-Day Free Trial

Data & sources

Counts checked November 6, 2026. Study counts come from PubMed searches on human studies, clinical trials, systematic reviews and meta-analyses. The product count is the on-market labels in the NIH Dietary Supplement Label Database, and the review estimate is that count times the reviews a typical graded product carries. The library figures come from our own database. See how Rala grades supplements.