Guide
How to get a personalized longevity protocol
A personalized protocol is a day you can follow: what to take, when, what to stop, and how your food, training and sleep fit around it, with your medications, goals and test results accounted for, and updated when they change. Ten kinds of tool promise some version of that. Here is what each one does, where it stops, and what it costs.
By Robert DeuPree. Published 19 September 2026. Prices and features are taken from each company's own website as of September 2026 and will change; check before you buy.
The short version
Most tools solve one slice. Databases tell you what the research says about an ingredient. Raters tell you whether a bottle is good quality. Blood panels and wearables measure you. Clinics give you a doctor. Protocol apps and podcast stacks give you somebody else's routine. Each is honest about its slice. What none of them does is take everything you already are, your supplements, your prescriptions, your goals, your numbers, and turn it into one day that keeps up with you. That is the gap a protocol engine exists to fill, and it is the gap Reverse Age Lab was built for.
The ten options
Asking an AI chatbot
ChatGPT, Gemini, Claude, Copilot
What it does well. Explains any ingredient in plain English, answers follow up questions, drafts questions for your doctor. Free or about $20 a month.
Where it stops. Forgets you between conversations, treats a mouse study and a human trial alike, does not know what is on any product's label, and gives doses with the same confidence whether they are right or wrong. It cannot check your whole stack against your medications, and nothing updates when your life changes.
Cost: Free to $20 a month. Best for: Learning what a supplement is before you buy it.
An evidence database
Examine.com
What it does well. Grades the human research on hundreds of supplements, ingredient by ingredient, with a research team and no products to sell. Examine+ is about $29 a month, or less prepaid for a year.
Where it stops. It knows the ingredient, not you. It does not hold your medications, goals or test results, does not rate the products on the shelf, and does not turn its grades into a day you can follow.
Cost: About $29 a month. Best for: Checking whether the science behind one ingredient is real.
A supplement rater
SuppCo (part of Function Health since May 2026)
What it does well. Scans a product and scores the brand and the bottle on quality signals, tracks what you take, and scores your stack against expert built protocols. Free, with a Pro tier of roughly $39 to $59 a year.
Where it stops. The score is about the product's quality, not about whether you should take it. It does not build a timed day, does not read your blood work, and does not bring diet and exercise into the picture.
Cost: Free; Pro $39 to $59 a year. Best for: Weeding low quality brands out of a stack you already have.
A blood panel membership
Function Health, InsideTracker
What it does well. Measures you. Function runs 160 plus lab tests a year with a clinician summary from $365 a year. InsideTracker pairs a $149 membership with tests of about $340 each and turns the results into recommendations.
Where it stops. Numbers are the start of a protocol, not the protocol. The advice that comes back is written for the biomarker, not for the rest of your stack, and you still have to decide what to take, when, and what to stop. A protocol engine can read these exact results if you upload them.
Cost: $365 to about $500 a year. Best for: Finding out what your blood actually says.
A longevity clinic
Lifeforce
What it does well. A real clinician. Lifeforce draws 50 plus biomarkers at home every three months, holds a consultation each time, and can prescribe. About $149 a month plus a $349 first diagnostic.
Where it stops. The price, and four touch points a year. Between visits your supplements, sleep and diet change and the plan does not. Many members also find the supplement advice leans on the clinic's own store.
Cost: About $149 a month plus $349. Best for: Anyone who wants a doctor in the loop and can afford one.
A wearable
WHOOP, Oura
What it does well. Measures sleep, recovery, heart rate variability and activity every day. WHOOP memberships run $199 to $359 a year; an Oura ring is about $349 plus $69.99 a year.
Where it stops. A wearable prescribes nothing. It tells you your sleep was short; it does not tell you which supplement is keeping you up, or that two things in your cabinet do the same job. Its numbers are most useful when something else reads them.
Cost: $199 to $359 a year, plus the device. Best for: Seeing whether a change is working.
A curated protocol app
Longevity Deck, Nuvo
What it does well. Packages protocols from podcasts and researchers into something you can track. Longevity Deck lists 150 plus protocols, free, with no account. Nuvo scores biological age from biomarkers and coaches from there.
Where it stops. The protocol is somebody else's. It was built for a 40 year old man with no medications, and it does not know that you take three.
Cost: Free to a few dollars a month. Best for: Trying a routine a researcher you trust already follows.
Copying a podcast stack
Huberman, Attia, Rhonda Patrick, Bryan Johnson
What it does well. Costs nothing but the supplements, and the people behind these stacks read the research seriously.
Where it stops. The stack was designed for its owner. Bryan Johnson takes over a hundred pills a day with a medical team checking his blood. Copying a list without the checking is how people end up with four sources of magnesium and a supplement that fights their prescription.
Cost: Free, plus the supplements. Best for: Ideas, not instructions.
A functional medicine practitioner
Naturopaths, functional medicine clinics
What it does well. Sits with you, orders tests, and writes a plan that accounts for your history. The gold standard for complicated cases.
Where it stops. Typically a few hundred dollars a visit, weeks between visits, and the plan lives on paper until the next one. Some practices also sell the supplements they recommend.
Cost: A few hundred dollars a visit. Best for: Complex conditions, and anything a licensed professional should handle.
A personalized vitamin subscription
Quiz based vitamin packs
What it does well. A quiz, then a monthly pack of the company's own pills.
Where it stops. The company grading your needs is the company selling the fix. The quiz rarely asks about medications, and the answer is always something from their catalogue.
Cost: $30 to $100 a month. Best for: Convenience, if you already know what you need.
What is left over, and how Reverse Age Lab handles it
Take the slices above and what is missing is the part in the middle: something that reads all of it about one person and writes the day. Reverse Age Lab is that part. A member fills in a health profile: goals, health history, every supplement and medication, allergies, diet, exercise and sleep. They can upload blood work and other test results from any lab, and connect a watch, ring or scale. Rala, the patent pending AI behind the service, grades every product on six evidence tiers from human studies, thousands of real reviews and what a fixed panel of biohackers take, then assembles one protocol by time of day: on waking, with the first meal, with the last meal, before sleep. It names the synergies, the conflicts, the duplicates and the products that cover two jobs at once. When a supplement, a medication, a goal or a lab result changes, the protocol is rebuilt.
Three things it is not. It is not a clinic: it does not diagnose, treat or replace a clinician, and the protocol is meant to be taken to yours. It is not a store: it sells no supplements and links out to retailers, so nothing on the list is there because of a margin. And it is not finished: the evidence it reads is published human research, but the system itself has not yet been the subject of an independent outcome study, which is why the free trial exists. Membership is $19.99 a month or $179 a year with a 7 day free trial; full details are on the pricing page and the plain answers on whether it is legit.
If you already follow a famous stack
We have read the well known ones against the evidence, product by product: Andrew Huberman, Peter Attia, Rhonda Patrick, Bryan Johnson's Blueprint, Dave Asprey and Ben Greenfield. For the general question of what to take, start with the longevity supplements with real evidence and which supplements should not be taken together.
Questions people ask
What is a personalized longevity protocol?
A daily plan built from your own health profile: what to take, when to take it, what to stop, and how your diet, exercise and sleep fit around it. It accounts for your medications, allergies, goals and test results, and it changes when they do. A list of popular supplements is not a protocol; a protocol is the list applied to one person.
Do I need a blood test before I can get a protocol?
No. A blood test makes a protocol better, and a good protocol engine will read the results you already have from any lab. But a protocol can start from your goals, your current supplements, your medications and your habits, and add the numbers when you have them.
Can ChatGPT build a supplement protocol?
It can explain ingredients well and draft a plan that reads convincingly. It cannot remember you between sessions, grade the strength of the evidence, check your whole stack against your medications, or update the plan when something changes, and it states wrong doses as confidently as right ones. Treat it as a research assistant, not a protocol.
Which option is the cheapest way to get a real protocol?
Copying a podcast stack is free and a curated protocol app is free or nearly so, but neither is built for you. Among tools that build from your own profile, Reverse Age Lab is $19.99 a month or $179 a year with a 7 day free trial, and it sells no supplements. A longevity clinic with a clinician is about ten times that.
What does Reverse Age Lab do that the others do not?
It builds one daily protocol from a member's whole health profile: supplements, medications, conditions, allergies, goals, diet, exercise, uploaded test results and wearable data. It grades every product on six evidence tiers from human studies, thousands of real reviews and biohacker evidence, flags conflicts, duplicates and timing, and rebuilds the protocol whenever anything changes. It sells no supplements. It is not a medical service and does not replace a clinician.
Can I use more than one of these together?
Yes, and most serious people do. A common combination is a blood panel or wearable to measure, an evidence database to read, and a protocol engine to turn the measurements and the evidence into a day. Reverse Age Lab reads uploaded test results and connects to wearables for exactly that reason.
About the comparisons on this page
Every company named here is a serious product used by people we respect, and several of them, a blood panel, a wearable, an evidence database, work well alongside a protocol. Descriptions and prices come from each company's own public pages as of September 2026. Nothing here was paid for, and no company was consulted. If a fact is out of date, write to support@reverseagelab.net and it will be corrected.